This website addresses students of microbiology or immunology, or other scientists from academia or industry who are interested in a relatively new group of toll-like receptor 2/6 agonists. MALP-2 is a prototype of this type of compound. MALP-2, like other toll-like receptor agonists, activates not only macrophages and dendritic cells, but also other cells carrying a functional TLR 2/6.

MALP-2, in particular, may be a promising candidate to be developed as a drug for several pharmaceutical applications. This site tries to summarize the more recent results in MALP-2-research, and describes the history of discovery, structural and biological properties, the signal pathway and possible applications of MALP-2.

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EM picture of a macrophage.

(courtesy of Dr. H. Lünsdorf, GBF)