|This website addresses
students of microbiology or immunology, or other scientists
from academia or industry who are interested in a relatively
new group of toll-like receptor 2/6 agonists. MALP-2
is a prototype of this type of compound. MALP-2, like
other toll-like receptor agonists, activates not only
macrophages and dendritic cells, but also other cells
carrying a functional TLR 2/6.
MALP-2, in particular, may be a promising candidate
to be developed as a drug for several pharmaceutical applications.
This site tries to summarize the more recent results in
MALP-2-research, and describes the history of discovery,
structural and biological properties, the signal pathway
and possible applications of MALP-2.
picture of a macrophage.
(courtesy of Dr. H. Lünsdorf, GBF)